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Delta Sleep-Inducing Peptide

SleepEvidence Level: researchNot FDA-approved; ongoing research in sleep medicine and stress management.
Peptide #13

DSIP, or Delta Sleep-Inducing Peptide, is a naturally occurring peptide discovered in the brain, known primarily for its role in sleep regulation and stress reduction. Comprising nine amino acids, DSIP has garnered significant interest due to its unique ability to influence sleep patterns, mood regulation, and overall neurological health.

Alternative Names:

DSIP

Overview

Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring neuropeptide known for its involvement in sleep regulation, stress reduction, and overall neurological health.

How It Works

DSIP promotes delta-wave sleep, modulates neurotransmitter levels, and regulates the HPA axis.

Clinical Effects

Enhances sleep quality, reduces sleep latency, regulates disturbed sleep patterns, reduces stress and anxiety, enhances mood stability, and potentially improves cognitive functions.

Therapeutic Applications

Studied for sleep disorders, stress and anxiety management, neurodegenerative diseases, and cognitive health.

Research Studies

Clinical Trials

Limited human trials conducted, indicating initial safety and efficacy for sleep improvement.

Preclinical Studies

Preclinical research shows potential in improving sleep architecture, reducing stress biomarkers, and neuroprotective effects.

Frequently Asked Questions

Is DSIP legally available? Yes, DSIP is legally available for research purposes from specialized suppliers but is not approved for clinical use. Have human trials been conducted with DSIP? Limited human trials have been conducted, indicating initial safety and efficacy for sleep improvement, but more comprehensive research is necessary. What are the potential side effects of DSIP? Preclinical and limited human studies report minimal side effects. However, thorough long-term safety profiles require further investigation. How is DSIP typically administered? DSIP is generally administered via subcutaneous injections in research settings, with dosage specifics varying based on experimental protocols. Can DSIP be combined with other peptides or treatments? Interactions between DSIP and other peptides or treatments remain largely unstudied and should be explored cautiously within controlled research contexts. Does DSIP cause dependency or withdrawal? Currently, no evidence suggests DSIP causes dependency or withdrawal, but more comprehensive studies are needed to confirm this.

Quick Information

Safety Information

Safety Profile

Comprehensive safety, efficacy, and dosage guidelines remain undetermined.

Contraindications

Side Effects: Minimal side effects reported in preclinical and limited human studies. Safety Profile: Comprehensive safety, efficacy, and dosage guidelines remain undetermined.

Side Effects

Minimal side effects reported in preclinical and limited human studies.

Research References

Graf, M.V., et al. (1984). Sleep-inducing effects of DSIP. Neuroscience & Biobehavioral Reviews. Pollmächer, T., et al. (1987). Effects of delta sleep-inducing peptide (DSIP) on sleep and the secretion of growth hormone in healthy volunteers. Psychoneuroendocrinology. Dreher, J., et al. (1989). Delta sleep-inducing peptide influences stress-induced adrenocorticotropic hormone and cortisol release. Neuropsychobiology.

Additional Resources