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Epithalon

LongevityEvidence Level: researchNot FDA-approved, research use only
Peptide #05

Epithalon is a synthetic tetrapeptide derived from the naturally occurring pineal gland hormone, epithalamin. It is recognized for its anti-aging and longevity-promoting properties, supporting cellular health, regulating the biological clock, and enhancing overall well-being. It stimulates telomerase activity, protecting telomeres from shortening and damage, and exhibits antioxidant, anti-inflammatory, and immunomodulatory properties.

Alternative Names:

Epitalon, Epithalamin

Overview

Epithalon is a synthetic tetrapeptide with anti-aging and longevity-promoting properties, supporting cellular health and regulating the biological clock.

How It Works

Epithalon promotes telomerase activity, maintaining and lengthening telomeres, slowing cellular aging, and potentially increasing cell lifespan.

Clinical Effects

Supports cellular health, regulates biological clock, enhances well-being, protects telomeres, exhibits antioxidant, anti-inflammatory, and immunomodulatory properties, influences hormonal balance, restores circadian rhythms, enhances sleep quality, improves stress resilience, reduces risk of cardiovascular conditions, neurodegenerative disorders, and certain cancers.

Therapeutic Applications

Anti-aging, lifespan extension, immune system support, sleep regulation, pineal gland health

Research Studies

Clinical Trials

Limited clinical studies conducted, showing promising initial safety and efficacy profiles.

Preclinical Studies

Animal models demonstrate significant lifespan extensions and delayed onset of age-related diseases.

Frequently Asked Questions

Is Epithalon legally available? Yes, for research purposes. Have human trials been conducted? Limited studies show promising safety and efficacy. Known side effects? Minimal reported. Administration? Subcutaneous or intramuscular injections. Can it be combined with other substances? Limited research on interactions. Does it permanently extend telomeres? Demonstrated temporary effects.

Quick Information

Safety Information

Safety Profile

Comprehensive safety, efficacy, and dosage guidelines remain undetermined.

Contraindications

Side Effects: Minimal side effects reported in preclinical and early-stage clinical trials. Safety Profile: Comprehensive safety, efficacy, and dosage guidelines remain undetermined.

Side Effects

Minimal side effects reported in preclinical and early-stage clinical trials.

Research References

Khavinson, V.K., et al. (2003). Peptide promotes overcoming of the division limit in human somatic cell. Bulletin of Experimental Biology and Medicine. Anisimov, V.N., et al. (2002). Effect of epithalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Mechanisms of Ageing and Development. Khavinson, V.K., & Malinin, V.V. (2002). Geroprotective effect of epithalamine (pineal gland peptide preparation) in elderly subjects. Bulletin of Experimental Biology and Medicine.

Additional Resources

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