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GHK-Cu

Hair & SkinEvidence Level: researchNot FDA-approved for specific therapeutic uses; significant scientific research underscores its promising capabilities.
Peptide #39

GHK-Cu, or Copper Tripeptide-1, is a naturally occurring tripeptide found in human plasma, saliva, and urine, known for its potent regenerative and anti-aging properties. Initially isolated for its remarkable ability to accelerate wound healing, GHK-Cu has since been extensively studied for its broader therapeutic potential, particularly in skin rejuvenation, hair growth, and overall anti-aging treatments.

Alternative Names:

Copper Tripeptide-1

Overview

GHK-Cu is a naturally occurring tri-peptide composed of glycine, histidine, and lysine, bonded with copper. Recognized for its potent regenerative, antioxidant, and anti-inflammatory properties, GHK-Cu has become highly valued in dermatology, aesthetics, and regenerative medicine.

How It Works

GHK-Cu significantly accelerates skin regeneration by stimulating collagen and elastin production, enhances glycosaminoglycan synthesis, and protects the skin from oxidative stress and environmental damage.

Clinical Effects

Accelerates skin regeneration, promotes hair growth, improves wound healing, reduces scar tissue formation, and enhances overall cellular health.

Therapeutic Applications

Skin rejuvenation, hair growth, wound healing, scar reduction, potential benefits in neurological conditions.

Research Studies

Clinical Trials

Limited human studies exist, demonstrating promising initial results in skin regeneration and hair growth.

Preclinical Studies

Animal and lab studies indicate significant improvements in hair density, thickness, and scalp health.

Frequently Asked Questions

Is GHK-Cu legally available? Yes, GHK-Cu is legally available for research purposes from specialized suppliers but is not approved for clinical use. Have human trials been conducted with GHK-Cu? Limited human studies exist, demonstrating promising initial results in skin regeneration and hair growth, although comprehensive research is necessary for clinical validation. What are potential side effects of GHK-Cu? Clinical trials indicate minimal side effects, primarily mild skin irritation in topical applications; however, thorough long-term safety assessments are needed. How is GHK-Cu typically administered? In research settings, GHK-Cu is commonly administered via topical application, subcutaneous injections, or incorporated into skincare formulations, with specific dosage protocols varying by study design. Can GHK-Cu be combined with other skincare ingredients or treatments? GHK-Cu is often studied in combination with other skincare and haircare ingredients, showing synergistic effects. However, controlled studies are required to thoroughly understand interactions and efficacy. Does GHK-Cu permanently reverse skin aging? GHK-Cu significantly improves skin appearance and health during treatment. Long-term maintenance of benefits may require ongoing use or periodic treatments.

Quick Information

Safety Information

Safety Profile

Strong safety profile demonstrated in both clinical and preclinical trials.

Contraindications

Side Effects: Minimal side effects, primarily mild skin irritation in topical applications. Safety Profile: Strong safety profile demonstrated in both clinical and preclinical trials.

Side Effects

Minimal side effects, primarily mild skin irritation in topical applications.

Research References

Pickart, L., et al. (2012). The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health. Oxidative Medicine and Cellular Longevity. Patt, L.M., et al. (2008). Copper peptide and skin. Dermatologic Therapy. Finkley, M.B., et al. (2005). Copper peptide and skin: clinical implications for aging skin. Clinical Dermatology.

Additional Resources