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Hexarelin

Weight LossEvidence Level: researchNot FDA-approved for general therapeutic use; ongoing research continues to explore its therapeutic potential, safety profile, and optimal clinical applications.
Peptide #18

Hexarelin is a synthetic peptide composed of six amino acids, designed to significantly stimulate the pituitary gland to release natural growth hormone (GH). Its powerful GH-releasing effects contribute to improved muscle growth, enhanced physical performance, and optimized metabolic health, making it appealing for clinical and research purposes.

Overview

Hexarelin is a potent synthetic hexapeptide known as a growth hormone secretagogue, specifically developed to stimulate the natural secretion of growth hormone (GH) from the pituitary gland. It has potential applications in improving body composition, enhancing lean muscle growth, reducing body fat, and supporting metabolic health.

How It Works

Hexarelin effectively stimulates the natural release of GH by binding to and activating growth hormone secretagogue receptors (GHSR) in the pituitary gland.

Clinical Effects

Improved muscle growth, enhanced physical performance, optimized metabolic health, improved insulin sensitivity, lipid metabolism, cardiovascular function, potential cardioprotective and neuroprotective effects.

Therapeutic Applications

Athletic performance enhancement, anti-aging medicine, therapeutic interventions for conditions characterized by GH deficiency or metabolic dysfunction, obesity and metabolic syndrome management, cardiovascular health.

Research Studies

Clinical Trials

Initial human clinical trials have shown promising results in GH stimulation, enhanced physical performance, and improved metabolic health.

Frequently Asked Questions

Is Hexarelin legally available? Hexarelin is legally available for research purposes through specialized suppliers but has not yet received FDA approval for general therapeutic use. Have human trials been conducted with Hexarelin? Yes, initial human clinical trials have shown promising results in GH stimulation, enhanced physical performance, and improved metabolic health. Further extensive research remains necessary to validate these outcomes fully. What are potential side effects of Hexarelin? Reported side effects are typically mild, including transient injection site reactions, increased hunger, and mild alterations in cortisol and prolactin levels. Comprehensive safety evaluations continue to assess its long-term profile. How is Hexarelin typically administered? Hexarelin is usually administered via subcutaneous injections in research settings, with dosage protocols tailored according to specific therapeutic objectives and clinical research protocols. Can Hexarelin be combined with other therapies? Controlled clinical studies are required to safely evaluate the effectiveness and interactions of Hexarelin when combined with other therapeutic interventions. Does Hexarelin offer permanent benefits? Hexarelin significantly stimulates GH release and enhances physical and metabolic functions during administration. Sustained therapeutic benefits typically require ongoing or periodic treatments, supported by comprehensive lifestyle management.

Quick Information

Safety Information

Safety Profile

Comprehensive safety evaluations continue to assess its long-term profile.

Contraindications

Side Effects: Transient injection site reactions, increased hunger, mild alterations in cortisol and prolactin levels. Safety Profile: Comprehensive safety evaluations continue to assess its long-term profile.

Side Effects

Transient injection site reactions, increased hunger, mild alterations in cortisol and prolactin levels.

Research References

Ghigo, E., et al. (1999). Growth hormone secretagogues (GHS): pharmacological and clinical aspects. Hormone Research. Broglio, F., et al. (2002). Growth hormone-releasing peptides and analogs: clinical perspectives. Trends in Endocrinology & Metabolism. Deghenghi, R., et al. (1994). Hexarelin (EP 23905), a potent growth hormone-releasing peptide, is devoid of interference with the pituitary-adrenal axis in man. Neuroendocrinology.

Additional Resources