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Thymosin Alpha-1

InflammationEvidence Level: researchResearch-only compound in the U.S., not FDA-approved for human use. Clinically approved and used in various international regions.
Peptide #20

Thymosin Alpha-1 is a naturally occurring peptide fragment derived from prothymosin alpha, widely studied for its role in immune system modulation. It supports immune resilience, enhances T-cell function, and assists in maintaining immune balance. It is used internationally to treat viral infections, immune deficiencies, and as an adjunct in cancer therapies.

Alternative Names:

Tα1, Zadaxin

Overview

Thymosin Alpha-1 is a synthetic peptide derived from a natural protein produced by the thymus gland, categorized as an immune modulator. It regulates the immune system by activating T-cells, stimulating natural killer cells, and balancing inflammatory cytokines.

How It Works

Thymosin Alpha-1 modulates immune responses, enhances adaptive immune function, supports antiviral and antibacterial activity, and influences autoimmune and chronic inflammatory conditions.

Clinical Effects

Enhances immune responses, manages autoimmune conditions, improves resistance to infections, reduces pathological inflammation, and exhibits antiviral and potential anti-cancer properties.

Therapeutic Applications

Immune modulation, antiviral therapies, autoimmune disease management, chronic viral infections, and chronic inflammatory diseases.

Research Studies

Clinical Trials

Numerous human clinical trials globally have demonstrated positive outcomes in immune support, antiviral therapies, and autoimmune disease management.

Preclinical Studies

Consistently report improved immune health, resistance to infections, and enhanced overall immunity.

Frequently Asked Questions

Is Thymosin Alpha-1 legally available? Yes, internationally for clinical and research purposes but not FDA-approved in the U.S. Have human trials been conducted? Yes, globally with positive outcomes. What are potential side effects? Typically minimal and mild. How is it administered? Via subcutaneous injections. Can it be combined with other therapies? Yes, frequently studied in combination. Does it permanently enhance immune function? Benefits require ongoing or periodic treatments.

Quick Information

Safety Information

Safety Profile

Comprehensive long-term safety studies are ongoing.

Contraindications

Side Effects: Typically minimal and mild, such as transient injection site reactions or mild flu-like symptoms. Safety Profile: Comprehensive long-term safety studies are ongoing.

Side Effects

Typically minimal and mild, such as transient injection site reactions or mild flu-like symptoms.

Research References

Goldstein, A.L., & Goldstein, A.L. (2009). Thymosin α1: a peptide with multifunctional properties beneficial in cancer, viral infections, and chronic inflammation. Expert Opinion on Biological Therapy. Sheridan, W.P., et al. (2004). Thymosin alpha 1 for the treatment of hepatitis B virus infection: a meta-analysis of randomized controlled trials. Antiviral Therapy. Zhang, X., et al. (2019). Thymosin alpha 1 inhibits the progression of colorectal cancer through modulation of the immune microenvironment. Cancer Science.

Additional Resources

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