Hair Regrowth That Works: PRP, Peptides, and Profitable Protocols for Your Practice

Hair thinning and scalp issues are no longer just cosmetic concerns—they’re among the top reasons patients seek out aesthetic and regenerative care [1]. By offering effective, evidence-based hair restoration solutions like topical therapies and Platelet-Rich Plasma (PRP), clinics can serve a massive, underserved market while creating recurring revenue streams.

When delivered in a comprehensive protocol, PRP and growth factor topicals can slow shedding, stimulate new growth, and improve scalp health—without the need for surgery or long-term pharmaceuticals [2].

• Use PRP Injections into the Scalp – Stimulate dormant follicles and increase circulation.
• Apply Growth Factor Topicals – Support scalp microbiome and improve follicular health.
• Add Red Light Therapy (LLLT) – Enhance blood flow and reduce inflammation.
• Include Nutritional & Hormonal Testing – Rule out internal causes (thyroid, iron, hormones).
• Create 3–6 Month Protocols – Offer bundled programs for long-term consistency and results.

• PRP (Platelet-Rich Plasma) – Uses the patient’s own platelets to promote growth factor release and follicle stimulation [2] [3].
• Exosome Scalp Serums – Advanced regenerative topicals to activate dormant follicles [4].
• Peptide-Based Topicals (e.g., GHK-Cu, PTD-DBM) – Support hair anchoring, shaft strength, and dermal papilla regeneration [5] [6].
• Minoxidil Alternatives – New formulations that work without shedding or irritation [7] [8].
• Biotin, Zinc & DHT Blocker Supplements – Supportive add-ons for internal optimization [9] [10].

• Hair Density and Shedding: PRP injections have been shown to improve hair density and reduce shedding after multiple sessions. Studies indicate a significant increase in hair thickness and count, making it a promising treatment for androgenic alopecia [2] [3].
• Safety and Efficacy: PRP is biocompatible and low-risk, using the patient's own blood components to stimulate hair growth. Clinical trials have demonstrated its effectiveness in both men and women with androgenic alopecia.

• Peptides and Exosomes: Topical peptides and exosomes have been found to improve follicular activity and hair thickness. These advanced regenerative topicals support hair anchoring and dermal papilla regeneration, enhancing overall scalp health [4].
• Minoxidil Alternatives: New formulations aim to provide similar benefits without the side effects associated with traditional minoxidil, such as shedding or irritation [7] [8].

• Scalp Circulation and Regrowth: LLLT has been shown to improve scalp circulation and support hair regrowth in androgenic alopecia. It enhances blood flow and reduces inflammation, making it a complementary treatment to PRP and topicals [11].

• High ROI Protocols: Scalp programs can range from $1,500–$4,000+ for 3–6 sessions.
• Repeatable Revenue: Maintenance sessions and topical refills drive recurring income.
• Strong Patient Satisfaction: Especially when results are documented via photos and scans.
• Men & Women Seek These Services: Market to postpartum women, men 30–60, and patients with thyroid/autoimmune conditions.

• Use FDA-cleared PRP kits and injectables – Ensure compliance and safety.
• Offer Scalp Analysis Tools – Use photography, dermoscopy, or trichoscopy to track results.
• Train Staff in Injection Techniques – Consistent depth and spacing are key to success.

• Highlight Real Patient Stories – Use social proof and before/after visuals.
• Create Signature Programs – “Hair Restoration Bootcamp” or “Root Revival Protocol” branding.
• Bundle with Other Aesthetic Services – Especially facial anti-aging, hormones, or gut health.

• Series Packages – Sell in bundles of 3–6 treatments with optional topicals.
• Membership Tie-In – Include scalp maintenance in ongoing beauty/wellness memberships.
• Retail Opportunity – Carry physician-grade hair growth topicals and shampoos.

1. Nestor MS, Ablon G, Gade A, Han H, Fischer DL. Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics. J Cosmet Dermatol. 2021;20(12):3759-3781.
2. Li M, Qu K, Lei Q, Chen M, Bian D. Effectiveness of Platelet-Rich Plasma in the Treatment of Androgenic Alopecia: A Meta-Analysis. Aesthetic Plast Surg. 2024 Mar;48(5):977-984.
3. Conde Montero E, Fernández Santos ME, Suárez Fernández R. Platelet-rich plasma: applications in dermatology. Actas Dermosifiliogr. 2015.
4. Gupta AK, Wang T, Rapaport JA. Systematic review of exosome treatment in hair restoration: Preliminary evidence, safety, and future directions. J Cosmet Dermatol. 2023;22(9):2424-2433.
5. Parikh AK, Tan IJ, Wolfe SM, Cohen BA. Advances in Topical Therapies for Clinically Relevant and Prevalent Forms of Alopecia. Life (Basel). 2024;14(12):1577.
6. Lee WJ, Sim HB, Jang YH, Lee SJ, Kim do W, Yim SH. Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth. Ann Dermatol. 2016;28(4):438-43.
7. Mehta A, Motavaf M, Raza D, McLure AJ, Osei-Opare KD, Bordone LA, Gru AA. Revolutionary Approaches to Hair Regrowth: Follicle Neogenesis, Wnt/ß-Catenin Signaling, and Emerging Therapies. Cells. 2025;14(11):779.
8. Gupta AK, Talukder M, Venkataraman M, Bamimore MA. Minoxidil: a comprehensive review. J Dermatolog Treat. 2022;33(4):1896-1906.
9. Rosenthal A, Conde G, Greco JF, Gharavi NM. Management of androgenic alopecia: a systematic review of the literature. J Cosmet Laser Ther. 2024;26(1-4):1-16.
10. Almohanna HM, Ahmed AA, Tsatalis JP, Tosti A. The Role of Vitamins and Minerals in Hair Loss: A Review. Dermatol Ther (Heidelb);9(1):51-70.
11. Avci P et al. Low-Level Laser Therapy for Treatment of Hair Loss. Lasers Surg Med. 2014;46(2):144–151.
12. Alves R, Grimalt R. Randomized Placebo-Controlled, Double-Blind Study of PRP in Androgenetic Alopecia. Dermatol Surg. 2016;42(4):491–497.